GRAVIMETRIC FILLING MACHINES

GRAVIMETRIC FILLING MACHINES

High-precision gravimetric fillers achieve ±0.05% accuracy via load cell technology. Handles viscous/foamy/aerated liquids. 500CPH max. FDA/CE/ATEX compliant.

  • Brand： glzon
  • Model： GZM

Product Essence: Mass-Based Precision Beyond Volumetric Limits

Shanghai Guangzhi Gravimetric Fillers overcome density variations with ±0.05% mass accuracy – mastering foamy detergents, aerated sauces, and shear-sensitive biologics that defeat volumetric systems. Featuring multi-cell load arrays (OIML Class 0.5), AI density compensation, and GMP/ATEX-ready builds, they achieve <0.01% giveaway while eliminating bubble errors, temperature drift, and recipe changeover waste.

Core Technology Innovations

1. Scientific Mass Control

ComponentTechnologyPerformance
Multi-Cell Load System4× OIML R60 Class 0.5 load cells±0.02% linearity error
Loss-in-Weight ControlReal-time flow feedback±0.05% setpoint accuracy
AI Density CompensationAuto-adjusts for SG variationsCompensates ±20% density shifts
Anti-VibrationActive seismic dampersRejects 95% floor vibration

2. Zero-Waste Architecture

Critical Features:

  • Dribble Phase Optimization: 50 L/min → 0.5 L/min transition

  • Residual Control: ≤0.1g material loss/nozzle

  • Overfill Prevention: Dual-redundant load cutoff

3. Material-Specific Engineering

Liquid ChallengeGuangzhi Solution
Foaming (detergents)Vacuum-assisted filling
Aeration (sauces)Pulsed pressure filling
Shear Sensitivity (mAbs)Low-speed peristaltic dosing
Static (solvents)Conductive paths + ionizing bars

Technical Specifications

ModelPharma Micro-FillerIndustrial Macro-FillerATEX Chemical Filler
Accuracy±0.02% (1g-5kg)±0.05% (1-100kg)±0.1% (5-1000kg)
Throughput200 fills/hour500 fills/hour300 fills/hour
Max. Density Shift±15% compensated±20% compensated±15% compensated
Container TypesVials/cartridgesPails/drumsIBCs/ISO tanks
Material Contact316L EP + USP VI316L + PTFEHastelloy C276
Power110V/0.5kW380V/3.5kW24VDC Ex ia
CalibrationAuto-span with NIST wtsSemi-auto with test weightsRemote calibration
Footprint (L×W×H)1000×800×1500mm2500×1200×2200mm3000×1500×2500mm

Industry-Specific Solutions

Pharmaceuticals

  • 21 CFR Part 11 electronic records

  • Isolator integration (ISO Class 5)

  • Single-use flow path option

Food & Sauces

  • USDA-compliant materials

  • Allergen purge protocol

  • CIP at 85°C

Chemicals & Solvents

  • ATEX Zone 1/21 certification

  • Vapor recovery >99%

  • Static control (<10⁵ Ω)

Cosmetics

  • Perfume alcohol compatibility

  • Anti-foam pulsed filling

Smart Control Ecosystem

10" HMI with AI Process Optimizer

Key Modules:

  • OEE Dashboard:

    • Material consumption vs target

    • Vibration interference alerts

    • Energy per fill (kWh/kg)

  • Self-Diagnostics:

    • Load cell drift detection

    • Filter clogging prediction

Operational Impact

Global Vaccine Manufacturer:

  • Challenge: ±3% fill variation in lipid nanoparticles (density shifts)

  • Solution: Gravimetric filler with AI density compensation

  • Results:
    ▶ ±0.08% accuracy for $500k/L materials
    ▶ Zero batch rejection in 12 months
    ▶ ROI: 3 months

Certifications & Upgrades

Global Compliance:

  • OIML R60 Class 0.5

  • FDA 21 CFR 210/211

  • ATEX 2014/34/EU (Zone 1)

  • ISO 9001:2015

Advanced Modules:

ModuleFunction
Inline RheometerReal-time viscosity (±2 cP)
Robotic TaringAuto-container weight learning
AR Maintenance GuideHoloLens-assisted calibration
Carbon Trackerkg CO₂ per tonne filled analytics

Support & Service

24/7 Metrology Support:

  • Remote diagnostics via IIoT gateway

  • Critical Spares Dispatch ≤48h:

    • Load cells (OIML Class 0.5)

    • Dribble valves

    • Vibration dampers

  • Performance Validation:

    • NIST-traceable weight certification

    • Material adhesion optimization

Where Every Milligram Matters
Shanghai Guangzhi Gravimetric Fillers: Engineering absolute precision for the world’s most valuable fluids – from vaccines to nano-suspensions. ⚖️

label: Gravimetric Filling Systems ±0.05% Accuracy Loss-in-Weight Multi-Industry Shanghai Guangzhi